IGLL1 anticorps

N° du produit ABIN2462601

Détail du produit anti-IGLL1 anticorps

Antigène: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGLL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IGLL1.

Information d'application

Indications d'application: IGLL1 antibody can be used for detection of IGLL1 by ELISA at 1:62500. IGLL1 antibody can be used for detection of IGLL1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store IGLL1 antibody at -20 °C.

Détails sur IGLL1

Antigène: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Autre désignation: IGLL1 (IGLL1 Produits)

Synonymes: anticorps 14.1, anticorps AGM2, anticorps CD179b, anticorps IGL1, anticorps IGL5, anticorps IGLJ14.1, anticorps IGLL, anticorps IGO, anticorps IGVPB, anticorps VPREB2, anticorps IGLV, anticorps IGLL1, anticorps MGC151892, anticorps Igll1, anticorps BB139905, anticorps Igl-5, anticorps Igll, anticorps Lambda5, anticorps immunoglobulin lambda like polypeptide 1, anticorps immunoglobulin lambda-like polypeptide 1, anticorps IGLL1, anticorps Igll1

Sujet: The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in its gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made.The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 19 kDa

ID gène: 3543

NCBI Accession: NP_064455

UniProt: P15814

Pathways: Regulation of Cell Size