AOC2 anticorps

N° du produit ABIN2462830

Détail du produit anti-AOC2 anticorps

Antigène: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AOC2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AOC2.

Information d'application

Indications d'application: AOC2 antibody can be used for detection of AOC2 by ELISA at 1:312500. AOC2 antibody can be used for detection of AOC2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AOC2 antibody at -20 °C.

Détails sur AOC2

Antigène: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Autre désignation: AOC2 (AOC2 Produits)

Synonymes: anticorps DAO2, anticorps RAO, anticorps AOC2, anticorps AOC3, anticorps aoc3, anticorps wu:fa94a08, anticorps wu:fe14c05, anticorps zgc:113006, anticorps amine oxidase, copper containing 2, anticorps amine oxidase, copper containing 2 (retina-specific), anticorps membrane primary amine oxidase-like, anticorps retina-specific copper amine oxidase, anticorps AOC2, anticorps Aoc2, anticorps LOC100353051, anticorps aoc2

Sujet: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine.Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 84 kDa, 81 kDa

ID gène: 314

NCBI Accession: NP_033720

UniProt: O75106