TAPBP anticorps

N° du produit ABIN2462853

Détail du produit anti-TAPBP anticorps

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAPBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAPBP.

Information d'application

Indications d'application: TAPBP antibody can be used for detection of TAPBP by ELISA at 1:12500. TAPBP antibody can be used for detection of TAPBP by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TAPBP antibody at -20 °C.

Détails sur TAPBP

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Autre désignation: TAPBP (TAPBP Produits)

Synonymes: anticorps SI:dZ179B20.1, anticorps SI:dZ179B20.3, anticorps SI:dZ179B20.7, anticorps mhc1uda, anticorps mhc1ufa, anticorps tpsn, anticorps zgc:109814, anticorps tapbp, anticorps TAPBP, anticorps D17Wsu91e, anticorps TPN, anticorps NGS17, anticorps TAPA, anticorps TPSN, anticorps TAP binding protein (tapasin), tandem duplicate 1, anticorps TAP binding protein, anticorps tapbp.1, anticorps tapbp, anticorps TAPBP, anticorps Tapbp

Sujet: TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Poids moléculaire: 46 kDa, 44 kDa

ID gène: 6892

NCBI Accession: NP_003181

UniProt: O15533