SEPN1 anticorps
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- Antigène Voir toutes SEPN1 Anticorps
- SEPN1 (Selenoprotein N, 1 (SEPN1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SEPN1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEPN1.
- Top Product
- Discover our top product SEPN1 Anticorps primaire
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- Indications d'application
- SEPN1 antibody can be used for detection of SEPN1 by ELISA at 1:1562500. SEPN1 antibody can be used for detection of SEPN1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SEPN1 antibody at -20 °C.
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- Antigène
- SEPN1 (Selenoprotein N, 1 (SEPN1))
- Autre désignation
- SEPN1 (SEPN1 Produits)
- Synonymes
- anticorps CFTD, anticorps MDRS1, anticorps RSMD1, anticorps RSS, anticorps SELN, anticorps 1110019I12Rik, anticorps AI414492, anticorps SePN, anticorps cb686, anticorps wu:fb06g01, anticorps wu:fb73d02, anticorps wu:fv41b08, anticorps zgc:101091, anticorps selenoprotein N, anticorps SELENON, anticorps Selenon, anticorps selenon
- Sujet
- SEPN1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Mutations in SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome.This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Poids moléculaire
- 58 kDa
- ID gène
- 57190
- NCBI Accession
- NP_996809
- Pathways
- Skeletal Muscle Fiber Development
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