ZP4 anticorps

N° du produit ABIN2463282

Détail du produit anti-ZP4 anticorps

Antigène: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZP4 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZP4.

Information d'application

Indications d'application: ZP4 antibody can be used for detection of ZP4 by ELISA at 1:1562500. ZP4 antibody can be used for detection of ZP4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZP4 antibody at -20 °C.

Détails sur ZP4

Antigène: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Autre désignation: ZP4 (ZP4 Produits)

Synonymes: anticorps ZPB, anticorps xlZPB, anticorps lzpb-a, anticorps MGC154827, anticorps zbp, anticorps zp1, anticorps ZBP, anticorps TAC4, anticorps MGC154888, anticorps ZP1, anticorps Zp-4, anticorps ZP3-ALPHA, anticorps ZP, anticorps Zp-X, anticorps zona pellucida glycoprotein 4 S homeolog, anticorps zona pellucida glycoprotein 4, anticorps zona pellucida glycoprotein 4 L homeolog, anticorps zp4.S, anticorps zp4, anticorps ZP4, anticorps zp4.L, anticorps Zp4

Sujet: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 49 kDa

ID gène: 57829

NCBI Accession: NP_067009

UniProt: Q12836