CDKN2B anticorps

N° du produit ABIN2463682

Détail du produit anti-CDKN2B anticorps

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN2B est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDKN2B.

Information d'application

Indications d'application: CDKN2B antibody can be used for detection of CDKN2B by ELISA at 1:2500. CDKN2B antibody can be used for detection of CDKN2B by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDKN2B antibody at -20 °C.

Détails sur CDKN2B

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Autre désignation: CDKN2B (CDKN2B Produits)

Synonymes: anticorps p14-INK4b, anticorps cdk4l, anticorps ink4b, anticorps mts2, anticorps p15, anticorps p15ink4b, anticorps tp15, anticorps CDK4I, anticorps INK4B, anticorps MTS2, anticorps P15, anticorps TP15, anticorps p15INK4b, anticorps AV083695, anticorps INK4b, anticorps p15(INK4b), anticorps CDKN2A, anticorps cyclin dependent kinase inhibitor 2B, anticorps Cyclin-dependent kinase 4 inhibitor B, anticorps cyclin-dependent kinase inhibitor 2B, anticorps cyclin-dependent kinase inhibitor 2B L homeolog, anticorps cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4), anticorps CDKN2B, anticorps cdn2b, anticorps cdkn2b, anticorps cdkn2b.L, anticorps Cdkn2b

Sujet: CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition.

Poids moléculaire: 15 kDa

ID gène: 1030

NCBI Accession: NP_004927

UniProt: P42772

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases