CRYGC anticorps

N° du produit ABIN2463921

Détail du produit anti-CRYGC anticorps

Antigène: CRYGC (Crystallin, gamma C (CRYGC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYGC est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CRYGC.

Information d'application

Indications d'application: CRYGC antibody can be used for detection of CRYGC by ELISA at 1:62500. CRYGC antibody can be used for detection of CRYGC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CRYGC antibody at -20 °C.

Détails sur CRYGC

Antigène: CRYGC (Crystallin, gamma C (CRYGC))

Autre désignation: CRYGC (CRYGC Produits)

Synonymes: anticorps Cryg, anticorps Cryg3, anticorps Len, anticorps CCL, anticorps CRYG3, anticorps CTRCT2, anticorps Cryg-5, anticorps ccl, anticorps cryg3, anticorps MGC84008, anticorps CRYGC, anticorps crystallin, gamma C, anticorps crystallin gamma C, anticorps crystallin gamma C L homeolog, anticorps gamma-crystallin C, anticorps Crygc, anticorps CRYGC, anticorps crygc.L, anticorps LOC100069179

Sujet: Crystallins are the dominant structural components of the vertebrate eye lens.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Poids moléculaire: 21 kDa

ID gène: 1420

NCBI Accession: NP_066269

UniProt: P07315