PARP1 anticorps

N° du produit ABIN2476185

Cité dans 3 publications. Cet anticorps anti-PARP1 Monoclonal Souris (Clone A6-4-12) (ABIN2476185) détecte spécifiquement PARP1 dans WB, ELISA, IF, IP, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Drosophila melanogaster, Hamster et Xenopus laevis.

Aperçu rapide pour PARP1 anticorps (ABIN2476185)

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivité: Humain, Souris, Rat, Drosophila melanogaster, Hamster, Xenopus laevis

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PARP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: A6-4-12

Détail du produit anti-PARP1 anticorps

Réactivité croisée: Mouche des fruits (Drosophila melanogaster), Hamster, Souris, Rat (Rattus), Xenopus laevis

Attributs du produit: Purified IgG

Purification: Purified

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Références pour anticorps anti-PARP1 (ABIN2476185)

Pinton, Manente, Murer, De Marino, Mutti, Moro: "PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." dans: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, (2013) (PubMed).

Harris, Jakob, Taucher-Scholz, Dianov, Becherel, Lavin: "Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage." dans: Human molecular genetics, Vol. 18, Issue 21, pp. 4102-17, (2009) (PubMed).

Freire, dAdda Di Fagagna, Wu, Pedrazzi, Stagljar, Hickson, Jackson: "Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha." dans: Nucleic acids research, Vol. 29, Issue 15, pp. 3172-80, (2001) (PubMed).

Détails sur PARP1

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Autre désignation: POLY(ADP-RIBOSE) POLYMERASE-1

ID gène: 142

UniProt: P09874

Pathways: Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location