GABRA1 anticorps (Cytoplasmic Domain)
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- Antigène Voir toutes GABRA1 Anticorps
- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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Épitope
- AA 368-419, Cytoplasmic Domain
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GABRA1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- Detects ~55 kDa. Does not cross-react with GABA A Receptor Alpha2 or other GABA-A Receptors based on KO validation data.
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Protein G Purified
- Immunogène
- Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA A Receptor Alpha5.
- Clone
- S415-24
- Isotype
- IgG1
- Top Product
- Discover our top product GABRA1 Anticorps primaire
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- Indications d'application
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- Commentaires
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A 1:100 dilution of ABIN2485752 was sufficient for detection of GABA-A R, Alpha5 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
- Autre désignation
- GABA A Receptor (GABRA1 Produits)
- Synonymes
- anticorps ECA4, anticorps EJM, anticorps EJM5, anticorps zgc:153566, anticorps Gabra-1, anticorps gamma-aminobutyric acid type A receptor alpha1 subunit, anticorps gamma-aminobutyric acid (GABA) A receptor, alpha 1, anticorps gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, anticorps gamma-aminobutyric acid receptor subunit alpha-1, anticorps GABRA1, anticorps Gabra1, anticorps gabra1, anticorps LOC100653509
- Sujet
- The GABA A Receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2). Recent research shows their usage in investigating side effects of drugs and the effects of learning and memory. Inverse agonists of the Alpha5 subunit may be useful in the treatment of Alzheimer's Disease (3).
- ID gène
- 2558
- NCBI Accession
- NP_000801
- UniProt
- P31644
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