EPH Receptor A7 anticorps (pTyr791)
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- Antigène Voir toutes EPH Receptor A7 (EPHA7) Anticorps
- EPH Receptor A7 (EPHA7)
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Épitope
- pTyr791
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EPH Receptor A7 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- The antibody detects endogenous levels of EPHA7only when phosphorylated at tyrosine 791.
- Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogène
- EPHA7 (phospho Tyr791) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y (p)-T-T) derived from Human EPHA7 .
- Isotype
- IgG
- Top Product
- Discover our top product EPHA7 Anticorps primaire
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- Indications d'application
- Western Blot: 1:500~1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store antibody at -20°C for up to one year.
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- Antigène
- EPH Receptor A7 (EPHA7)
- Autre désignation
- EPHA7 (EPHA7 Produits)
- Synonymes
- anticorps fc51g03, anticorps wu:fc51g03, anticorps si:dkey-23k6.1, anticorps EHK3, anticorps HEK11, anticorps Cek11, anticorps Ebk, anticorps Ehk3, anticorps Hek11, anticorps Mdk1, anticorps CEPHA7, anticorps EPH receptor A7, anticorps eph receptor A7, anticorps ephrin type-B receptor 1-B, anticorps Eph receptor A7, anticorps EPHA7, anticorps epha7, anticorps LOC100166161, anticorps Epha7
- Sujet
- Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.
- Poids moléculaire
- 112 kDa
- ID gène
- 2045
- NCBI Accession
- NP_004431
- UniProt
- Q15375
- Pathways
- Signalisation RTK
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