RACGAP1 anticorps (pSer387)

N° du produit ABIN2568176

Détail du produit anti-RACGAP1 anticorps

Antigène: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Épitope: pSer387

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RACGAP1 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous level of GTPase Activating Protein only when phosphorylated at serine 387.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: GTPase Activating Protein (phospho Ser387) antibody was raised against a peptide sequence around phosphorylation site of serine 387 (R-I-S (p)-G-C) derived from Human GTPase Activating Protein.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur RACGAP1

Antigène: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Autre désignation: GTPase Activating Protein (RACGAP1 Produits)

Synonymes: anticorps CYK4, anticorps HsCYK-4, anticorps ID-GAP, anticorps MgcRacGAP, anticorps cyk-4, anticorps id-gap, anticorps mgcracgap, anticorps RACGAP1, anticorps MGC121578, anticorps Gap, anticorps RasGAP, anticorps Rasa, anticorps GAPX, anticorps AI227039, anticorps AI327394, anticorps Band25, anticorps GTPase, anticorps gtl11, anticorps mKIAA1478, anticorps wu:fb92c08, anticorps zgc:77839, anticorps Rac GTPase activating protein 1, anticorps rac GTPase-activating protein 1, anticorps Rac GTPase activating protein 1 L homeolog, anticorps RAS p21 protein activator 1, anticorps Rac GTPase-activating protein 1, anticorps si:ch1073-416j23.1, anticorps RACGAP1, anticorps racgap1, anticorps racgap1.L, anticorps racgap1.2.L, anticorps racgap1.2, anticorps Rasa1, anticorps Racgap1, anticorps si:ch1073-416j23.1

Sujet: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation.

Poids moléculaire: 72 kDa

ID gène: 29127

NCBI Accession: NP_001119575

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor