IL12A anticorps

N° du produit ABIN2568235

Détail du produit anti-IL12A anticorps

Antigène: IL12A (Interleukin 12 alpha (IL12A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12A est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: IL-12A antibody is human specific. IL-12A antibody will not cross-react with IL-12B.

Purification: IL-12A antibody is affinity chromatography purified via peptide column.

Immunogène: IL-12A antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IL-12A.

Isotype: IgG

Information d'application

Indications d'application: IL-12A antibody can be used for detection of IL-12A by Western blot at 0.5 - 1 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-12A antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IL-12A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur IL12A

Antigène: IL12A (Interleukin 12 alpha (IL12A))

Autre désignation: IL-12A (IL12A Produits)

Synonymes: anticorps CLMF, anticorps IL-12A, anticorps NFSK, anticorps NKSF1, anticorps P35, anticorps CLMF2, anticorps IL-12B, anticorps NKSF, anticorps NKSF2, anticorps p40, anticorps Il-12b, anticorps Il12p40, anticorps Il-12p40, anticorps Il12, anticorps IL-12p40, anticorps IL-12p35, anticorps Il-12a, anticorps Ll12a, anticorps p35, anticorps IL12p35, anticorps Il-12 p35, anticorps IL12p40, anticorps IL12, anticorps IL-12 p35, anticorps interleukin 12A, anticorps interleukin 12B, anticorps interleukin 12b, anticorps interleukin 12a, anticorps Interleukin 12 level, anticorps IL12A, anticorps IL12B, anticorps Il12b, anticorps Il12a, anticorps IL12, anticorps il12a

Sujet: IL-12A is subunit of the cytokine IL-12 which acts on T- and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 35-kD subunit and a 40-kD subunit that is a member of the cytokine receptor family (1). IL-12 is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells (1,2). The responses of lymphocytes to IL-12 are mediated by the activator of transcription protein STAT4 (2). Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity (3).

Poids moléculaire: Predicted: 22 kDa

Observed: 22 kDa

ID gène: 3592

NCBI Accession: NP_000873

UniProt: P29459

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation