Protein Tob1 (TOB1) (pSer164) anticorps

N° du produit ABIN2568512

Détail du produit

Antigène: Protein Tob1 (TOB1)

Épitope: pSer164

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: The antibody detects endogenous levels of TOB1 only when phosphorylated at serine 164.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: TOB1 (phospho Ser164) antibody was raised against a peptide sequence around phosphorylation site of Serine 164 (A-V-S (p)-P-T) derived from Human TOB1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détail du antigène

Antigène: Protein Tob1 (TOB1)

Autre désignation: TOB1 (TOB1 Produits)

Synonymes: anticorps Tob, anticorps Trob, anticorps APRO5, anticorps APRO6, anticorps PIG49, anticorps TOB, anticorps TROB, anticorps TROB1, anticorps tob1, anticorps tob1l, anticorps wu:fb54d02, anticorps wu:fb98h12, anticorps wu:fd15f10, anticorps zgc:65837, anticorps transducer of ErbB-2.1, anticorps transducer of ERBB2, 1, anticorps transducer of ERBB2, 1a, anticorps transducer of ERBB2, 1 S homeolog, anticorps transducer of ERBB2, 1b, anticorps Tob1, anticorps TOB1, anticorps tob1a, anticorps tob1.S, anticorps tob1b

Sujet: This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.

Poids moléculaire: 40 kDa

ID gène: 10140

NCBI Accession: NP_001230806

UniProt: P50616