CYP2A6 anticorps (C-Term, pSer472)

N° du produit ABIN264498

Détail du produit anti-CYP2A6 anticorps

Antigène: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Épitope: C-Term, pSer472

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CYP2A6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to Cytochrome p450 2A6.

Attributs du produit: Synonyms: CYP2A3, Cytochrome P450 2A6, CYPIIA6, CYPIIA3, Coumarin 7-hydroxylase

Purification: Purified

Immunogène: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized withSynthetic peptide conjugated to ovalbumin derived from the C-terminus of CYP2A6 andmouse myeloma Ag8563 cells. Antigen identical in CYP2A6, 2A7 and 2A13.

Clone: F16 P2 D8

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Immunohistochemistry on paraffin sections. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CYP2A6

Antigène: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Autre désignation: CYP2A6 (CYP2A6 Produits)

Synonymes: anticorps CPA6, anticorps CYP2A, anticorps CYP2A3, anticorps CYPIIA6, anticorps P450C2A, anticorps P450PB, anticorps cyp2a6, anticorps cytochrome P450 family 2 subfamily A member 6, anticorps cytochrome P450 2A6, anticorps cytochrome P450 family 2 subfamily A member 6 L homeolog, anticorps CYP2A6, anticorps cyp2a6.L

Sujet: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP2A6 is a liver enzyme that metabolizes a number of drugs and a variety of procarcinogens, though it is primarily responsible for the metabolism of nicotine, the major addictive agent in tobacco. CYP2A6 inactivates nicotine to cotinine, and then cotinine to 3-hydroxycotinine. Differences in CYP2A6 genotypes are related to nicotine dependence, and may influence smoking habits and withdrawal symptoms in individuals that are quitting smoking. This suggests that an individualized smoking cessation program may be designed based on CYP2A6 genotypes.Synonyms: CYP2A3, CYPIIA3, CYPIIA6, Coumarin 7-hydroxylase, Cytochrome P450 2A6

ID gène: 1548

UniProt: P11509