CCR8 anticorps (Extracellular Loop)

N° du produit ABIN265001

Détail du produit anti-CCR8 anticorps

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Épitope: AA 183-201, Extracellular Loop

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR8 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to CCR8.

Purification: Purified

Immunogène: Antibody raised against a synthetic peptide corresponding to amino acids 183 to 201 of the human CCR8. Peptide sequence is located in the second extracellular loop.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 0.5 to 1 μg/mL. Detects an approximately 50 kDa band in human spleentissue lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline solution containing 0.02 % sodium azide as a preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.

Détails sur CCR8

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Autre désignation: CDw198 / CCR8 (CCR8 Produits)

Synonymes: anticorps CC-CKR-8, anticorps CCR-8, anticorps CDw198, anticorps CKRL1, anticorps CMKBR8, anticorps CMKBRL2, anticorps CY6, anticorps GPRCY6, anticorps TER1, anticorps C-C, anticorps C-C CKR-8, anticorps CKR-8, anticorps Cmkbr8, anticorps mCCR8, anticorps C-C motif chemokine receptor 8, anticorps chemokine (C-C motif) receptor 8, anticorps CCR8, anticorps Ccr8

Sujet: CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR11-4. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains5. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1

ID gène: 1237

NCBI Accession: NP_005192

UniProt: P51685