PPAP2A anticorps

N° du produit ABIN265043

Détail du produit anti-PPAP2A anticorps

Antigène: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPAP2A est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody recognizes Lysophospholipid Phosphatase (LPP) 1/1A.

Purification: Purified

Immunogène: Synthetic peptide derived from the LPP1 protein.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C. Can be shipped at 2-8 °C.

Détails sur PPAP2A

Antigène: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Autre désignation: PPAP2A / LPP1 (PPAP2A Produits)

Synonymes: anticorps PPAP2A, anticorps wun, anticorps LLP1a, anticorps LPP1, anticorps PAP-2a, anticorps PAP2, anticorps Hic53, anticorps Hpic53, anticorps LPP-1, anticorps mPAP, anticorps PAP2A, anticorps PAP2a2, anticorps phospholipid phosphatase 1, anticorps phosphatidic acid phosphatase type 2A, anticorps phospholipid phosphatase 1 L homeolog, anticorps PLPP1, anticorps plpp1, anticorps Ppap2a, anticorps plpp1.L, anticorps Plpp1

Sujet: Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma.Synonyms: Lipid phosphate phosphohydrolase 1, PAP2-alpha, PAP2a, Phosphatidate phosphohydrolase type 2a, Phosphatidic acid phosphatase 2a

ID gène: 8611

NCBI Accession: NP_003702

UniProt: O14494

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway