TNFRSF4 anticorps (APC)

N° du produit ABIN2656909

Détail du produit anti-TNFRSF4 anticorps (APC)

Antigène: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF4 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Réactivité croisée: Chimpanzé

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: Ber-ACT35 (ACT35)

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur TNFRSF4

Antigène: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Autre désignation: CD134 (TNFRSF4 Produits)

Synonymes: anticorps TNFRSF4, anticorps ACT35, anticorps CD134, anticorps Ly-70, anticorps Ox40, anticorps TXGP1L, anticorps Txgp1, anticorps OX40, anticorps TNF receptor superfamily member 4, anticorps tumor necrosis factor receptor superfamily, member 4, anticorps TNFRSF4, anticorps Tnfrsf4

Sujet: CD134, also known as OX40 and TNFRSF14, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints