TNFRSF4 anticorps (AA 29-214)
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- Antigène Voir toutes TNFRSF4 Anticorps
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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Épitope
- AA 29-214
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TNFRSF4 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human OX40 (AA: extra 29-214) expressed in HEK293 cells.
- Clone
- 7B5E10
- Isotype
- IgG2a
- Top Product
- Discover our top product TNFRSF4 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Autre désignation
- OX40 (TNFRSF4 Produits)
- Synonymes
- anticorps TNFRSF4, anticorps ACT35, anticorps CD134, anticorps Ly-70, anticorps Ox40, anticorps TXGP1L, anticorps Txgp1, anticorps OX40, anticorps TNF receptor superfamily member 4, anticorps tumor necrosis factor receptor superfamily, member 4, anticorps TNFRSF4, anticorps Tnfrsf4
- Sujet
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Aliases: TNFRSF4, ACT35, CD134, IMD16, TXGP1L
- Poids moléculaire
- 29.3 kDa
- ID gène
- 7293
- HGNC
- 7293
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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