DLL4 anticorps

N° du produit ABIN2658126

Détail du produit anti-DLL4 anticorps

Antigène: DLL4 (delta-Like 4 (DLL4))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp DLL4 est non-conjugé

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography.

Clone: HMD4-1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur DLL4

Antigène: DLL4 (delta-Like 4 (DLL4))

Autre désignation: delta-Like 4 (DLL4 Produits)

Synonymes: anticorps hdelta2, anticorps Delta4, anticorps si:ch211-244p18.5, anticorps zgc:136596, anticorps delta like canonical Notch ligand 4, anticorps delta-like 4 (Drosophila), anticorps DLL4, anticorps Dll4, anticorps dll4

Sujet: The Notch receptors and their ligands are highly conserved from invertebrates to mammals. Delta-like 4 (DLL4) is one of four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. DLL4 is reported to be essential for the regulation of angiogenesis. In thymus, DLL4 is an essential Notch1 ligand responsible for T cell lineage commitment.

Pathways: Signalisation Notch