Fc gamma RII (CD32) anticorps (APC)

N° du produit ABIN2658611

Détail du produit

Antigène: Fc gamma RII (CD32)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: APC

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: FUN-2

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détail du antigène

Antigène: Fc gamma RII (CD32)

Autre désignation: CD32 (CD32 Produits)

Synonymes: anticorps CD32, anticorps CD32B, anticorps FCG2, anticorps FCGR2, anticorps IGFR2, anticorps FCGR2B, anticorps AI528646, anticorps F630109E10Rik, anticorps Fc[g]RII, anticorps FcgRII, anticorps Fcgr2, anticorps Fcgr2a, anticorps Fcr-2, anticorps Fcr-3, anticorps Ly-17, anticorps Ly-m20, anticorps LyM-1, anticorps Lym-1, anticorps FCRII, anticorps FcRII, anticorps Fc fragment of IgG receptor IIb, anticorps Fc receptor, IgG, low affinity IIb, anticorps FCGR2B, anticorps Fcgr2b

Sujet: CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).