HVEM anticorps (PE)
-
- Antigène Voir toutes HVEM (TNFRSF14) Anticorps
- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
-
Reactivité
- Souris
-
Hôte
-
Hamster arménien
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp HVEM est conjugé à/à la PE
-
Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Clone
- HMHV-1B18
- Isotype
- IgG
- Top Product
- Discover our top product TNFRSF14 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- Antigène
- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
- Autre désignation
- CD270 (TNFRSF14 Produits)
- Synonymes
- anticorps ATAR, anticorps CD270, anticorps HVEA, anticorps HVEM, anticorps LIGHTR, anticorps TR2, anticorps Atar, anticorps HveA, anticorps Hvem, anticorps Tnfrs14, anticorps TNF receptor superfamily member 14, anticorps tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), anticorps Tnfrsf14, anticorps TNFRSF14
- Classe de substances
- Viral Protein
- Sujet
- Herpes Virus Entry Mediator (HVEM, TR2) is a type I transmembrane protein of TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HAS) entry. Binding of HSV viral envelope glycoprotein D to this receptor has been shown to be part of the viral entry mechanism. It is expressed on most cell types, including T cells, B cells, monocytes, neutrophils, and dendritic cells. It is also found in brain, heart, kidney, liver, and other organs. The ligands of HVEM are LIGHT, BTLA, LTα, and CD160. HVEM activates NF-kB through the TNF-related cytokine LIGHT to serve as a costimulatory pathway during T cell activation. HVEM also functions as a ligand for the Ig superfamily members B and T lymphocyte attenuator (BTLA) and CD160 to deliver a coinhibitory signal and limit inflammatory responses initiated by T cells. HVEM plays an important role in regulating lymphocyte activation and homeostasis in immune responses.
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
-