PRDM1 anticorps

N° du produit ABIN2664076

Détail du produit anti-PRDM1 anticorps

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRDM1 est non-conjugé

Application: Flow Cytometry (FACS)

Réactivité croisée: Souris

Purification: The antibody was purified by affinity chromatography.

Clone: ROS195G

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur PRDM1

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Autre désignation: Blimp-1 (PRDM1 Produits)

Synonymes: anticorps GB11750, anticorps CG5249, anticorps Dmel\\CG5249, anticorps blimp-1, anticorps dBlimp-1, anticorps dBlimp1, anticorps Blimp-1, anticorps Blimp1, anticorps nrd, anticorps prdm1, anticorps ubo, anticorps wu:fb99c12, anticorps zgc:91885, anticorps MGC52536, anticorps PRDM1, anticorps blimp1, anticorps xblimp1, anticorps prdi-bf1, anticorps BLIMP1, anticorps PRDI-BF1, anticorps ZNFPR1A1, anticorps PR/SET domain 1, anticorps probable serine/threonine-protein kinase DDB_G0282963, anticorps CG5249 gene product from transcript CG5249-RF, anticorps blimp-1, anticorps PR domain containing 1a, with ZNF domain, anticorps PR domain 1 S homeolog, anticorps B lymphocyte induced maturation protein 1, anticorps PR domain 1, anticorps PR domain containing 1, with ZNF domain, anticorps PRDM1, anticorps LOC408295, anticorps Blimp-1, anticorps CpipJ_CPIJ007425, anticorps prdm1a, anticorps prdm1.S, anticorps prdm1, anticorps Prdm1

Sujet: Blimp-1 is a 98 Kd protein containing five Kuppel-type zinc finger domains that confer sequence specific DNA binding. It has been postulated to be a master regulator of terminal B cell differentiation. In the BCL-1 lymphoma model of differentiation from mature B cells to plasma cells, ectopic expression of Blimp-1 is sufficient to cause terminal differentiation manifested by loss of surface immunoglobulin, IgM secretion, expression of syndecan-1 and cessation of cell division. Recently, it is reported that Blimp-1 is also involved in T cell differentiation and T cell homeostasis and suppression of IL-2 production.

Pathways: Regulation of Muscle Cell Differentiation