CD131 anticorps

N° du produit ABIN2664200

Détail du produit anti-CD131 anticorps

Antigène: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD131 est non-conjugé

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography.

Clone: 1C1

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD131

Antigène: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Autre désignation: CD131 (CSF2RB Produits)

Synonymes: anticorps Csf2rb1, anticorps CSF2RB, anticorps cd131, anticorps cdw131, anticorps il3rb, anticorps il5rb, anticorps il-3rbc, anticorps CD131, anticorps CDw131, anticorps IL3RB, anticorps IL5RB, anticorps SMDP5, anticorps AI848964, anticorps AIC2B, anticorps Bc, anticorps Csfgmrb, anticorps Il3r, anticorps Il3rb, anticorps Il3rb1, anticorps Il5rb, anticorps colony stimulating factor 2 receptor beta common subunit, anticorps colony stimulating factor 2 receptor beta common subunit S homeolog, anticorps cytokine receptor common subunit beta-like, anticorps colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), anticorps CSF2RB, anticorps Csf2rb, anticorps csf2rb.S, anticorps CRCBL, anticorps csf2rb

Sujet: CD131, also known as the IL-3R common β subunit (βC), is a 95-120 kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common β subunit associates with the specific α subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. The 1C1 antibody is a non-blocking antibody.

Pathways: Signalistation JAK/STAT