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TNFRSF12A anticorps
TNFRSF12A
Reactivité: Humain
IHC, FACS, Func
Hôte: Souris
Monoclonal
ITEM-1
unconjugated
N° du produit ABIN2664460
Détail du produit anti-TNFRSF12A anticorps
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Antigène
Voir toutes TNFRSF12A Anticorps
TNFRSF12A
(Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
Reactivité
Toutes les réactivités sur TNFRSF12A Anticorps
Humain
Hôte
Toutes les hôtes sur TNFRSF12A Anticorps
Souris
Clonalité
Toutes les clonalités sur TNFRSF12A Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers TNFRSF12A Anticorps
Cet anticorp TNFRSF12A est non-conjugé
Application
Tous les applications à travers TNFRSF12A Anticorps.
Immunohistochemistry (IHC), Flow Cytometry (FACS), Functional Studies (Func)
Purification
The antibody was purified by affinity chromatography.
Clone
ITEM-1
Isotype
IgG1 kappa
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Alternatives
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 104-118) antibody
TNFRSF12A
Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Singe, Roussette (Chauve-souris), Hamster
WB
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur TNFRSF12A
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Antigène
TNFRSF12A
(Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
Autre désignation
CD266 (TNFRSF12A Produits )
Synonymes
anticorps CD266, anticorps FN14, anticorps TWEAKR, anticorps AI255180, anticorps C87282, anticorps Fn14, anticorps HPIP, anticorps TWEAK-R, anticorps TweakR, anticorps TNF receptor superfamily member 12A, anticorps tumor necrosis factor receptor superfamily, member 12a, anticorps TNFRSF12A, anticorps Tnfrsf12a
Sujet
TWEAK receptor is also known as fibroblast growth factor inducible 14 kD protein (Fn14) or CD266. It is a 14 kD transmembrane protein that is expressed on a variety of tissue types. This receptor binds TWEAK and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The TWEAK receptor is rapidly induced during liver regeneration and m play a role in hepatocyte growth. TWEAK receptor engagement can induce cell death and may play a role in inflammation. The ITEM-1 antibody is useful for flow cytometric analysis, induction of tumor cells apoptosis or necrotic cell death, enhancing endothelial cell proliferation, and immunohistochemistry on frozen tissues.
Pathways
Apoptose , Regulation of Cell Size
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