TNFRSF12A anticorps
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- Antigène Voir toutes TNFRSF12A Anticorps
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TNFRSF12A est non-conjugé
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Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- ITEM-4
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product TNFRSF12A Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- Autre désignation
- CD266 (TNFRSF12A Produits)
- Synonymes
- anticorps CD266, anticorps FN14, anticorps TWEAKR, anticorps AI255180, anticorps C87282, anticorps Fn14, anticorps HPIP, anticorps TWEAK-R, anticorps TweakR, anticorps TNF receptor superfamily member 12A, anticorps tumor necrosis factor receptor superfamily, member 12a, anticorps TNFRSF12A, anticorps Tnfrsf12a
- Sujet
- CD266 is a 14 kD transmembrane protein known as TWEAK receptor (TWEAK-R) or fibroblast growth factor inducible 14 (Fn14). It is member 12A of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed at low levels in a variety of tissues, such as heart, placenta, lung, muscle, and pancreas. TWEAK-R binds TWEAK (CD255) and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The engagement of Fn14 can induce cell death and may play a role in inflammation, hepatocyte growth, and liver neoplasia.
- Pathways
- Apoptose, Regulation of Cell Size
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