CD200 anticorps

N° du produit ABIN2689078

Détail du produit anti-CD200 anticorps

Antigène: CD200

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD200 est non-conjugé

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: Reacts with a 40-45 kDa membrane glycoprotein also referred to as OX2. CD200 is a member of the immunoglobulin superfamily of proteins. It contains two Ig domains, a single transmembrane region and a short cytoplasmic tail. CD200 is expressed on resting and PMA-activated T- and B-cells, but not on NK cells, monocytes, granulocytes, or platelets. It has been found on a subset of CD34+ progenitor cells. Interaction of CD200 with its receptor on macrophages induces a downregulation of macrophage activity in a variety of tissues, suggesting a regulatory function. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of anti-CD200, clone MRC OX-104, staining on peripheral blood lymphocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD200 - Purified - Clone MRC OX-104 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: MRC OX

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD200 (ABIN2689078)

Wright, Jones, Puklavec, Brown, Barclay: "The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans." dans: Immunology, Vol. 102, Issue 2, pp. 173-9, (2001) (PubMed).

Hoek, Ruuls, Murphy, Wright, Goddard, Zurawski, Blom, Homola, Streit, Brown, Barclay, Sedgwick: "Down-regulation of the macrophage lineage through interaction with OX2 (CD200)." dans: Science (New York, N.Y.), Vol. 290, Issue 5497, pp. 1768-71, (2000) (PubMed).

Wright, Puklavec, Willis, Hoek, Sedgwick, Brown, Barclay: "Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function." dans: Immunity, Vol. 13, Issue 2, pp. 233-42, (2000) (PubMed).

Détails sur CD200

Antigène: CD200

Autre désignation: CD200 (CD200 Produits)

Synonymes: anticorps MOX1, anticorps MOX2, anticorps MRC, anticorps OX-2, anticorps CD200, anticorps Cspmo2, anticorps MRCOX2, anticorps Mox2, anticorps DKFZp459C0716, anticorps OX2, anticorps CD200 molecule, anticorps Cd200 molecule, anticorps CD200 antigen, anticorps CD200, anticorps Cd200

Sujet: Synonyms: OX2