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CD22 anticorps

CD22 Reactivité: Humain FACS, IHC (fro) Hôte: Souris Monoclonal HIB22 unconjugated
N° du produit ABIN2689094
  • Antigène Voir toutes CD22 Anticorps
    CD22 (CD22 Molecule (CD22))
    Reactivité
    • 153
    • 50
    • 24
    • 5
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 101
    • 61
    • 14
    Souris
    Clonalité
    • 124
    • 54
    Monoclonal
    Conjugué
    • 81
    • 15
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD22 est non-conjugé
    Application
    • 111
    • 71
    • 45
    • 38
    • 38
    • 18
    • 13
    • 11
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Marque
    BD Pharmingen™
    Attributs du produit
    Reacts with the 130-140 kDa glycosylated type I integral membrane protein present on the surface of mature B cells. CD22 is expressed in the cytoplasm of virtually all B cells except plasma cells. CD45RO antigen on T cells and CD75 antigen on B cells have been identified as ligands for CD22. CD22 has been reported to participate in B-cell activation and also as an adhesion molecule. Although the immunobiology of this antigen has not been fully elucidated, reports indicate that ligation of CD22 induces constitutive internalization of the molecule followed by complete degradation. Profile of peripheral blood lymphocytes analyzed on a BD FACScan™ .

    BD Pharmingen™ Purified Mouse Anti-Human CD22 - Purified - Clone HIB22 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    HIB22
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD22 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • Shan, Press: "Constitutive endocytosis and degradation of CD22 by human B cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 9, pp. 4466-75, (1995) (PubMed).

    Clark: "CD22, a B cell-specific receptor, mediates adhesion and signal transduction." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 11, pp. 4715-8, (1993) (PubMed).

  • Antigène
    CD22 (CD22 Molecule (CD22))
    Autre désignation
    CD22 (CD22 Produits)
    Synonymes
    anticorps A530093D23, anticorps Lyb-8, anticorps Lyb8, anticorps SIGLEC-2, anticorps SIGLEC2, anticorps siglec-2, anticorps CD22 antigen, anticorps CD22 molecule, anticorps Cd22, anticorps CD22
    Sujet
    Synonyms: BL-CAM
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