CD58 anticorps

N° du produit ABIN2689345

Détail du produit anti-CD58 anticorps

Antigène: CD58

Reactivité: Humain, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD58 est non-conjugé

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: Reacts with a 60-70 kDa membrane glycoprotein member of the immunoglobulin superfamily. CD58, also referred to as the lymphocyte function-associated antigen-3 (LFA-3), has a wide tissue distribution, being expressed on both hematopoietic and non-hematopoietic cells, including endothelial cells and fibroblasts. There are two isoforms of CD58: a glycosylphosphatidylinositol (GPI)-linked formed and a transmembrane form. Both isoforms may be expressed in the same cell type. Erythrocytes, however, only have the GPI-linked isoform. CD58 interacts with CD2 during cell adhesion. This binding can enhance antigen-specific T-cell activation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD58 - Purified - Clone 1C3 (also known as AICD58) - Isotype Mouse IgG2a, κ - Reactivity Hu, Dog - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: 1C3

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD58 (ABIN2689345)

Dengler, Hoffmann, Knolle, Albert-Wolf, Roux, Wallich, Meuer: "Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3)." dans: European journal of immunology, Vol. 22, Issue 11, pp. 2809-17, (1992) (PubMed).

Détails sur CD58

Antigène: CD58

Autre désignation: CD58 (CD58 Produits)

Synonymes: anticorps LFA-3, anticorps LFA3, anticorps ag3, anticorps CD58 molecule, anticorps CD58

Sujet: Synonyms: LFA-3