Interferon gamma anticorps

N° du produit ABIN2689588

Détail du produit anti-Interferon gamma anticorps

Antigène: Interferon gamma (IFNG)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Interferon gamma est non-conjugé

Application: Western Blotting (WB), ELISA, Neutralization (Neut)

Marque: BD Pharmingen™

Attributs du produit: The R4-6A2 antibody reacts with mouse interferon-γ (IFN-γ). The immunogen used to generate the R4-6A2 hybridoma was partially-purified mouse IFN-γ protein. This is a neutralizing antibody. This antibody is routinely tested by ELISA Capture. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Purified Rat Anti-Mouse IFN-γ - Purified - Clone R4-6A2 - Isotype Rat IgG1, κ - Reactivity Ms - 1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Partially-Purified Mouse IFN-gamma

Clone: R4

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-Interferon gamma (ABIN2689588)

Mo, Sarawar, Doherty: "Induction of cytokines in mice with parainfluenza pneumonia." dans: Journal of virology, Vol. 69, Issue 2, pp. 1288-91, (1995) (PubMed).

Sarawar, Sangster, Coffman, Doherty: "Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 3, pp. 1246-53, (1994) (PubMed).

Lucin, Pavić, Polić, Jonjić, Koszinowski: "Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands." dans: Journal of virology, Vol. 66, Issue 4, pp. 1977-84, (1992) (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." dans: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).

Sadick, Heinzel, Holaday, Pu, Dawkins, Locksley: "Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism." dans: The Journal of experimental medicine, Vol. 171, Issue 1, pp. 115-27, (1990) (PubMed).

Stevenson, Tam, Belosevic, van der Meide, Podoba: "Role of endogenous gamma interferon in host response to infection with blood-stage Plasmodium chabaudi AS." dans: Infection and immunity, Vol. 58, Issue 10, pp. 3225-32, (1990) (PubMed).

Détails sur Interferon gamma

Antigène: Interferon gamma (IFNG)

Autre désignation: IFN-gamma (IFNG Produits)

Synonymes: anticorps IFG, anticorps IFI, anticorps IFN-g, anticorps Ifg, anticorps IFNG2, anticorps IFN-gamma, anticorps IFN-G, anticorps IFNG, anticorps IFNgamma, anticorps TCRalpha, anticorps INF-G, anticorps ifng, anticorps interferon gamma, anticorps interferon, gamma 1-2, anticorps IFNG, anticorps Ifng, anticorps ifng1-2

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy