BCL10 anticorps
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- Antigène Voir toutes BCL10 Anticorps
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BCL10 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Attributs du produit
- Homo sapiens B-cell CLL/lymphoma 10 (BCL10)
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell.
- Clone
- 6A4
- Isotype
- IgG1
- Top Product
- Discover our top product BCL10 Anticorps primaire
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- Indications d'application
- WB 1:2000, IF 1:100, FLOW 1:100
- Commentaires
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
- Autre désignation
- BCL10 (BCL10 Produits)
- Synonymes
- anticorps CARMEN, anticorps CIPER, anticorps CLAP, anticorps c-E10, anticorps mE10, anticorps BCL10, anticorps AI132454, anticorps BCL-10, anticorps C81403, anticorps ME10, anticorps cE10, anticorps bcl10, anticorps B-cell CLL/lymphoma 10, anticorps B-cell lymphoma/leukemia 10-like, anticorps B cell leukemia/lymphoma 10, anticorps B-cell lymphoma/leukemia 10, anticorps BCL10, anticorps Bcl10, anticorps bcl10, anticorps LOC100223183
- Sujet
- This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
- Poids moléculaire
- 26.1 kDa
- ID gène
- 8915
- NCBI Accession
- NM_003921
- HGNC
- 8915
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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