CYP27A1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
DO NOT FREEZE!
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C.
Duan, Fu, Wang, Ni, Zhao: "Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens." dans: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 176, pp. 59-64, (2014) (PubMed).
Haag, Stadel, Zhou, Bachem, Möller, Debatin, Fulda: "Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells." dans: Gut, Vol. 60, Issue 2, pp. 225-37, (2011) (PubMed).
Korzekwa, Bah, Kurzynowski, Lukasik, Groblewska, Skarzynski: "Leukotrienes modulate secretion of progesterone and prostaglandins during the estrous cycle and early pregnancy in cattle: an in vivo study." dans: Reproduction (Cambridge, England), Vol. 140, Issue 5, pp. 767-76, (2011) (PubMed).
Antigène
CYP27A1
(Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
anticorps CP27, anticorps CTX, anticorps CYP27, anticorps Cyp27, anticorps P450C27, anticorps 1300013A03Rik, anticorps cytochrome P450 family 27 subfamily A member 1, anticorps cytochrome P450, family 27, subfamily a, polypeptide 1, anticorps cytochrome P450, family 27, subfamily A, polypeptide 1, anticorps sterol 26-hydroxylase, mitochondrial, anticorps CYP27A1, anticorps Cyp27a1, anticorps cyp27a1
Sujet
The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity.Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the CsA and is encoded by a single unique gene conserved from yeast to humans. CyPA is involved in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.Synonyms: 12-alpha-triol 27-hydroxylase, 5-beta-cholestane-3-alpha, 7-alpha, CYP27, Cytochrome P-450C27/25, Cytochrome P450 27, Sterol 26-hydroxylase, Sterol 27-hydroxylase, Vitamin D3-25-hydroxylase