Thyroglobulin anticorps

N° du produit ABIN2744777

Détail du produit anti-Thyroglobulin anticorps

Antigène: Thyroglobulin (TG)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thyroglobulin est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Human TG / Thyroglobulin

Purification: Protein G purified

Immunogène: Human thyroid follicular cells were used as the immunogen for this Thyroglobulin antibody.

Type of Immunogen: Cells

Clone: 6E1 or TGB05

Isotype: IgG1 kappa

Information d'application

Indications d'application: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IHC, IHC-P (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

Usage: Thyroglobulin is a 660  kDa dimeric pre-protein with mutiple glycosylation sites, detected at ~300  kDa in western blot. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for thyroglobulin antibody even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently thyroglobulin antibody negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Thyroglobulin antibody, combined with calcitonin antibody, can identify medullary carcinomas of the thyroid. Furthermore, thyroglobulin antibody, combined with TTF1 antibody, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. ELISA: Order BSA-free format for coating.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C to 8°C.

Détails sur Thyroglobulin

Antigène: Thyroglobulin (TG)

Autre désignation: TG / Thyroglobulin (TG Produits)

Synonymes: anticorps TG, anticorps cb717, anticorps AITD3, anticorps TGN, anticorps Tgn, anticorps cog, anticorps thyroglobulin, anticorps TG, anticorps tg, anticorps LOC701526, anticorps LOC701756, anticorps LOC100434297, anticorps Tg

Sujet: Name/Gene ID: TG

Synonyms: TG, AITD3, TDH3, Thyroglobulin, TGN

ID gène: 7038

Pathways: Thyroid Hormone Synthesis