Insulin anticorps

N° du produit ABIN2749217

Cet anticorps Souris Monoclonal détecte spécifiquement Insulin dans ELISA, IHC (p), ICC, RIA et Func. Il présente une réactivité avec des échantillons de Humain, Porc et Boeuf (Vache).

Aperçu rapide pour Insulin anticorps (ABIN2749217)

Antigène: Insulin (INS)

Reactivité: Humain, Porc, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Insulin est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Radioimmunoassay (RIA), Functional Studies (Func)

Clone: IN-05

Détail du produit anti-Insulin anticorps

Fonction: Anti-Insulin Purified Low Endotoxin

Réactivité croisée (Details): Human, Bovine, Porcine

Attributs du produit: The antibody IN-05 reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas, it is also present in tumors of B cell origin such as insulinoma.

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

niveau d'endotoxine: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogène: Porcine insulin.

Isotype: IgG1

Information d'application

Indications d'application: Functional application: The antibody IN-05 blocks binding of insulin to the receptor.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Conseil sur la manipulation: Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur Insulin

Antigène: Insulin (INS)

Autre désignation: Insulin

Sujet: Proinsulin,Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population.,IDDM, INS

ID gène: 3630

UniProt: P01308

Pathways: Signalisation NF-kappaB, Signalisation RTK, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation