CTDSP2 anticorps (Middle Region)
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- Antigène Voir toutes CTDSP2 Anticorps
- CTDSP2 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2 (CTDSP2))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Cheval, Boeuf (Vache), Lapin, Cobaye, Chien, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CTDSP2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ASYIFHPENA VPVQSWFDDM ADTELLNLIP IFEELSGAED VYTSLGQLRA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 91%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CTDSP2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CTDSP2
- Top Product
- Discover our top product CTDSP2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 271 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CTDSP2 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2 (CTDSP2))
- Autre désignation
- CTDSP2 (CTDSP2 Produits)
- Synonymes
- anticorps fb16c04, anticorps wu:fb16c04, anticorps zgc:77714, anticorps MGC68415, anticorps CTDSP2, anticorps OS4, anticorps PSR2, anticorps SCP2, anticorps AI586070, anticorps D10Ertd73e, anticorps OS-4, anticorps CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, anticorps CTD small phosphatase 2 L homeolog, anticorps CTD small phosphatase 2, anticorps ctdsp2, anticorps ctdsp2.L, anticorps CTDSP2, anticorps Ctdsp2
- Sujet
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CTDSP2 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.CTDSP2 negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. CTDSP2 is recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.CTDSP2 may contribute to the development of sarcomas.
Alias Symbols: OS4, PSR2, SCP2
Protein Interaction Partner: CDCA3, UBC, AR, SNAI1, POLR2A,
Protein Size: 271 - Poids moléculaire
- 31 kDa
- ID gène
- 10106
- NCBI Accession
- NM_005730, NP_005721
- UniProt
- O14595
- Pathways
- ER-Nucleus Signaling
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