CTDSP2 anticorps (Center)

N° du produit ABIN2855986

Détail du produit anti-CTDSP2 anticorps

Antigène: CTDSP2 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2 (CTDSP2))

Épitope: Center

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTDSP2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Macaque rhésus

Réactivité croisée (Details): Rhesus Monkey (100 %)

Attributs du produit: Rabbit Polyclonal antibody to CTDSP2 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2)
CTDSP2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CTDSP2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Commentaires:

Positive Control: 293T , mouse brain , PC-12

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CTDSP2

Antigène: CTDSP2 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2 (CTDSP2))

Autre désignation: CTDSP2 (CTDSP2 Produits)

Synonymes: anticorps fb16c04, anticorps wu:fb16c04, anticorps zgc:77714, anticorps MGC68415, anticorps CTDSP2, anticorps OS4, anticorps PSR2, anticorps SCP2, anticorps AI586070, anticorps D10Ertd73e, anticorps OS-4, anticorps CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, anticorps CTD small phosphatase 2 L homeolog, anticorps CTD small phosphatase 2, anticorps ctdsp2, anticorps ctdsp2.L, anticorps CTDSP2, anticorps Ctdsp2

Sujet: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

Cellular Localization: Nucleus

Poids moléculaire: 31 kDa

ID gène: 10106

Pathways: ER-Nucleus Signaling