NEDD4 anticorps (Middle Region)

N° du produit ABIN2774920

Détail du produit anti-NEDD4 anticorps

Antigène: NEDD4 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Cheval, Lapin, Chien, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEDD4 est non-conjugé

Application: Western Blotting (WB)

Séquence: SRRGSLQAYT FEEQPTLPVL LPTSSGLPPG WEEKQDERGR SYYVDHNSRT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NEDD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NEDD4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 900 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NEDD4

Antigène: NEDD4 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))

Autre désignation: NEDD4 (NEDD4 Produits)

Synonymes: anticorps NEDD4-1, anticorps RPF1, anticorps AA959633, anticorps AL023035, anticorps AU019897, anticorps E430025J12Rik, anticorps Nedd4-1, anticorps Nedd4a, anticorps mKIAA0093, anticorps CG32184, anticorps CG42279, anticorps CG7555, anticorps DNedd4, anticorps Dmel\\CG42279, anticorps Dmel_CG32184, anticorps Dmel_CG7555, anticorps dNedd4, anticorps dNedd4-1, anticorps nedd4, anticorps GB16853, anticorps NEDD4, anticorps Nedd4, anticorps neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase, anticorps neural precursor cell expressed, developmentally down-regulated 4, anticorps CG42279 gene product from transcript CG42279-RJ, anticorps E3 ubiquitin-protein ligase Nedd-4, anticorps E3 ubiquitin-protein ligase NEDD4, anticorps NEDD4, anticorps Nedd4, anticorps LOC411723, anticorps LOC100457150, anticorps nedd4, anticorps LOC100547485

Sujet: NEDD4 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. NEDD4 is involved in the budding of many viruses.
Alias Symbols: KIAA0093, MGC176705, RPF1, NEDD4-1
Protein Interaction Partner: RPO21, UBI4, UBC8, RNF7, SRC, POLR2A, NEDD4, CUL5, UBE2L3, UBE2D3, UBE2D1, UBC, FGFR1, SPT23, PTCH1, SMO, YOD1, TNK2, SNCA, GUCD1, FBXL18, ERBB3, CSNK1D, CCNH, RBX1, BTRC, CUL1, SKP1, PTEN, ARRDC3, MDM2, RAPGEF2, AMOTL1, POLR2M, RPAP2, EPRS, DIAPH1, DDX3X
Protein Size: 900

Poids moléculaire: 104 kDa

ID gène: 4734

NCBI Accession: NM_006154, NP_006145

UniProt: B4E2R7

Pathways: Signalisation Notch, Intracellular Steroid Hormone Receptor Signaling Pathway, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2