KIR3DL1 anticorps (Middle Region)

N° du produit ABIN2775346

Détail du produit anti-KIR3DL1 anticorps

Antigène: KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIR3DL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: EHFFLHKEGI SKDPSRLVGQ IHDGVSKANF SIGPMMLALA GTYRCYGSVT

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KIR3DL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human KIR3DL1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KIR3DL1

Antigène: KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))

Autre désignation: KIR3DL1 (KIR3DL1 Produits)

Synonymes: anticorps KIR3DL1, anticorps KIR3DL3, anticorps CD158E1, anticorps KIR, anticorps KIR3DL1/S1, anticorps NKAT3, anticorps NKB1, anticorps NKB1B, anticorps Kirl1, anticorps Kirl2, anticorps Krl1, anticorps killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1, anticorps uncharacterized LOC100437736, anticorps killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1, anticorps KIR3DL1, anticorps LOC100437736, anticorps Kir3dl1

Sujet: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
Alias Symbols: CD158E1, KIR, KIR3DL1/S1, NKAT3, NKB1, NKB1B
Protein Interaction Partner: env, RPS6KB1, HLA-B, CDK3,
Protein Size: 444

Poids moléculaire: 48 kDa

ID gène: 3811

NCBI Accession: NM_013289, NP_037421

UniProt: P43629