HDAC3 anticorps (C-Term)
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- Antigène Voir toutes HDAC3 Anticorps
- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HDAC3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against Hdac3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Rat
- Top Product
- Discover our top product HDAC3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 428 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- Autre désignation
- Hdac3 (HDAC3 Produits)
- Synonymes
- anticorps CG2128, anticorps DHDAC3, anticorps DmHDAC3, anticorps Dmel\\CG2128, anticorps Dromel_CG2128_FBtr0078767_hdac3_mORF, anticorps HDAC, anticorps HDAC3, anticorps Hdac 3, anticorps dHDAC3, anticorps dmHDA402, anticorps hdac3, anticorps HDm, anticorps hd3, anticorps RPD3, anticorps XRpd3, anticorps rpd3-2, anticorps HD3, anticorps RPD3-2, anticorps AW537363, anticorps zgc:55927, anticorps Histone deacetylase 3, anticorps histone deacetylase 3, anticorps histone deacetylase 3 S homeolog, anticorps HDAC3, anticorps hdac3, anticorps CNL05260, anticorps Hdac3, anticorps hdac3.S
- Sujet
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Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
Alias Symbols: Hdac3
Protein Interaction Partner: Cebpa, Hr,
Protein Size: 428 - Poids moléculaire
- 49 kDa
- ID gène
- 84578
- NCBI Accession
- NM_053448, NP_445900
- UniProt
- Q6P6W3
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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