SCN8A anticorps (C-Term)

N° du produit ABIN2776200

Détail du produit anti-SCN8A anticorps

Antigène: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN8A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KSSIFSFRGP GRFRDPGSEN EFADDEHSTV EESEGRRDSL FIPIRARERR

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SCN8A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human SCN8A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SCN8A

Antigène: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Autre désignation: SCN8A (SCN8A Produits)

Synonymes: anticorps CERIII, anticorps CIAT, anticorps EIEE13, anticorps MED, anticorps NaCh6, anticorps Nav1.6, anticorps PN4, anticorps AI853486, anticorps C630029C19Rik, anticorps dmu, anticorps med, anticorps mnd-2, anticorps mnd2, anticorps nmf2, anticorps nmf335, anticorps nmf58, anticorps nur14, anticorps seal, anticorps sodium voltage-gated channel alpha subunit 8, anticorps sodium channel, voltage-gated, type VIII, alpha, anticorps SCN8A, anticorps Scn8a

Sujet: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
Alias Symbols: MED, PN4, CIAT, NaCh6, CERIII, EIEE13, Nav1.6
Protein Size: 475

Poids moléculaire: 52 kDa

ID gène: 6334

NCBI Accession: NM_001177984, NP_001171455

UniProt: Q9UQD0

Pathways: Sensory Perception of Sound