SCN8A anticorps (Internal Region)

N° du produit ABIN6263505

Détail du produit anti-SCN8A anticorps

Antigène: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN8A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Nav1.6/SCN8A Antibody detects endogenous levels of total Nav1.6/SCN8A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Nav1.6/SCN8A, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SCN8A

Antigène: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Autre désignation: SCN8A (SCN8A Produits)

Synonymes: anticorps CERIII, anticorps CIAT, anticorps EIEE13, anticorps MED, anticorps NaCh6, anticorps Nav1.6, anticorps PN4, anticorps AI853486, anticorps C630029C19Rik, anticorps dmu, anticorps med, anticorps mnd-2, anticorps mnd2, anticorps nmf2, anticorps nmf335, anticorps nmf58, anticorps nur14, anticorps seal, anticorps sodium voltage-gated channel alpha subunit 8, anticorps sodium channel, voltage-gated, type VIII, alpha, anticorps SCN8A, anticorps Scn8a

Sujet:

Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.

Gene: SCN8A

Poids moléculaire: 225 kDa

ID gène: 6334

UniProt: Q9UQD0

Pathways: Sensory Perception of Sound