MTA1 anticorps (Middle Region)
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- Antigène Voir toutes MTA1 Anticorps
- MTA1 (Metastasis Associated 1 (MTA1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MTA1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- QADITDLLKE GEEDGRDQSR LETQVWEAHN PLTDKQIDQF LVVARSVGTF
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%
- Attributs du produit
- This is a rabbit polyclonal antibody against MTA1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human MTA1
- Top Product
- Discover our top product MTA1 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MTA1 (Metastasis Associated 1 (MTA1))
- Autre désignation
- MTA1 (MTA1 Produits)
- Synonymes
- anticorps Tex22, anticorps metastasis associated 1, anticorps metastasis associated 1 L homeolog, anticorps MTA1, anticorps Mta1, anticorps mta1.L
- Sujet
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This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: KRT40, LZTS2, IKZF1, SH3GL1, SAT1, RBBP4, MAGEA11, KPNA3, NOTCH2NL, KRTAP10-8, KHDRBS2, SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, UBC, SUZ12, EED, RNF2, HIC1, SOX2, HDAC2, HDAC1, HIST3H3, GATAD2B, MBD3, KDM1A, POLD3, MTA2, NR2C2, NR2C1, CHD4, UBE2I, HIST2H3C, B
Protein Size: 430 - Poids moléculaire
- 47 kDa
- ID gène
- 9112
- Pathways
- Chromatin Binding
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