Prostate Specific Antigen anticorps (Middle Region)

N° du produit ABIN971004

Détail du produit anti-Prostate Specific Antigen anticorps

Antigène: Prostate Specific Antigen (PSA)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prostate Specific Antigen est non-conjugé

Application: Western Blotting (WB)

Séquence: LRPGDDSSHD LMLLRLSEPA ELTDAVKVMD LPTQEPALGT TCYASGWGSI

Homologie: Dog: 77%, Human: 100%, Mouse: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against KLK3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 261 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Prostate Specific Antigen (ABIN971004)

Alzghoul, Hailat, Zivanovic, Que, Shah: "Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip." dans: Biosensors & bioelectronics, Vol. 77, pp. 491-8, (2015) (PubMed).

Détails sur Prostate Specific Antigen

Antigène: Prostate Specific Antigen (PSA)

Autre désignation: KLK3 (PSA Produits)

Synonymes: anticorps APS, anticorps KLK2A1, anticorps PSA, anticorps hK3, anticorps KLK3, anticorps Klk1c10l2, anticorps RSGK-50, anticorps RSKG-50, anticorps rGK-3, anticorps Kal-3, anticorps Kal3, anticorps Klk3, anticorps AAP-S, anticorps MP100, anticorps Psa, anticorps R74825, anticorps goku, anticorps kallikrein related peptidase 3, anticorps kallikrein 3, anticorps kallikrein 1-related peptidase C3, anticorps kallikrein B, plasma 1, anticorps aminopeptidase puromycin sensitive, anticorps KLK3, anticorps Klk1c3, anticorps Klkb1, anticorps Npepps

Sujet: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Alias Symbols: APS, KLK2A1, PSA, hK3
Protein Interaction Partner: ALB, PZP, SERPINA5, SERPINA1, SEMG2, SEMG1, PLG, PTHLH, IGFBP3, FN1, EPOR, SLPI, SERPINA3, A2M, POLR2A, AR, KAT5, RUVBL1, CTNNB1,
Protein Size: 261

Poids moléculaire: 26 kDa

ID gène: 354

NCBI Accession: NM_001648, NP_001639

UniProt: P07288

Pathways: Système du Complément