ATP7A anticorps (N-Term)

N° du produit ABIN2778125

Détail du produit anti-ATP7A anticorps

Antigène: ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Mouton, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP7A est non-conjugé

Application: Western Blotting (WB)

Séquence: MKKQIEAMGF PAFVKKQPKY LKLGAIDVER LKNTPVKSSE GSQQRSPSYQ

Specificité: The immunizing peptide used to raise this antibody is 100 % homologous to isoform 3 (503aa 54.3 kDa), 1 (1514aa, 165 kDa), 2 (1581aa, 172 kDa) and 5 (1422aa, 154 kDa) of human ATP7A.

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ATP7A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATP7A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1500 AAAA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATP7A

Antigène: ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))

Autre désignation: ATP7A (ATP7A Produits)

Synonymes: anticorps ATP7A, anticorps cal, anticorps wu:fc43e01, anticorps zgc:153422, anticorps zgc:158633, anticorps DDBDRAFT_0218568, anticorps DDBDRAFT_0235190, anticorps DDB_0218568, anticorps DDB_0235190, anticorps atpase, anticorps Atp7a, anticorps kal, anticorps atp7a, anticorps DSMAX, anticorps MK, anticorps MNK, anticorps SMAX3, anticorps Blo, anticorps DXHXS1608e, anticorps I14, anticorps Mo, anticorps blotchy, anticorps br, anticorps brindled, anticorps mottled, anticorps Mnk, anticorps ATPase copper transporting alpha, anticorps ATPase, Cu++ transporting, alpha polypeptide, anticorps P-type ATPase, anticorps ATP synthase subunit a, anticorps copper-transporting ATPase 1, anticorps ATP7A, anticorps atp7a, anticorps LOC100049514, anticorps Atp7a, anticorps LOC412379

Sujet: The ATP7A gene encodes the Menkes copper-translocating P-type ATPase, a ubiquitous protein that regulates the absorption of copper in the gastrointestinal tract. Inside cells, this protein has a dual function: it delivers copper to cuproenzymes in the Golgi compartment and effluxes excess copper. The trafficking mechanism and catalytic activity combine to facilitate absorption and intercellular transport of copper. Menkes disease, a systemic copper deficiency disorder, is caused by mutations in the ATP7A gene.
Alias Symbols: MK, MNK, DSMAX, SMAX3
Protein Interaction Partner: ACIN1, UBC, COMMD1, CLU, ATOX1, PDZD11, CP, GLRX,
Protein Size: 1500aa

Poids moléculaire: 163 kDa

ID gène: 538

NCBI Accession: NM_000052, NP_000043

UniProt: Q04656

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process