ELF3 anticorps (Middle Region)
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- Antigène Voir toutes ELF3 Anticorps
- ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Chien, Lapin, Cheval, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ELF3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TATPQSSHAS DSGGSDVDLD LTESKVFPRD GFPDYKKGEP KHGKRKRGRP
- Homologie
- Cow: 79%, Dog: 86%, Horse: 86%, Human: 79%, Mouse: 100%, Pig: 79%, Rabbit: 79%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against Elf3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of mouse Elf3
- Top Product
- Discover our top product ELF3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 371 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
- Autre désignation
- Elf3 (ELF3 Produits)
- Synonymes
- anticorps ert, anticorps esx, anticorps epr-1, anticorps ese-1, anticorps ESE-1, anticorps ESX, anticorps jen, anticorps EPR-1, anticorps ERT, anticorps E74 like ETS transcription factor 3, anticorps E74-like factor 3, anticorps elf3, anticorps Elf3, anticorps ELF3
- Sujet
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Elf3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. It acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity). It also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. IT represses KRT4 promoter activity (By similarity). It may play an important role in epithelial cell differentiation and tumorigenesis and may be a critical downstream effector of the ERBB2 signaling pathway (By similarity). It may be associated with mammary gland development and involution. It plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
Alias Symbols: ESE-1, ESX, jen
Protein Size: 371 - Poids moléculaire
- 41 kDa
- ID gène
- 13710
- NCBI Accession
- NM_007921, NP_031947
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