TNFRSF10A anticorps (C-Term)
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- Antigène Voir toutes TNFRSF10A Anticorps
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TNFRSF10A est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RAGTAGPGDA LYAMLMKWVN KTGRNASIHT LLDALERMEE RHAKEKIQDL
- Homologie
- Human: 100%, Mouse: 80%
- Attributs du produit
- This is a rabbit polyclonal antibody against TNFRSF10A. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product TNFRSF10A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 468 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- Autre désignation
- TNFRSF10A (TNFRSF10A Produits)
- Synonymes
- anticorps APO2, anticorps CD261, anticorps DR4, anticorps TRAILR-1, anticorps TRAILR1, anticorps TNFRSF10A, anticorps TNF receptor superfamily member 10a, anticorps tumor necrosis factor receptor superfamily member 26, anticorps tumor necrosis factor receptor superfamily, member 10a, anticorps TNFRSF10A, anticorps LOC510798
- Sujet
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This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Alias Symbols: APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1
Protein Interaction Partner: UBC, MARCH8, MARCH1, CFLAR, FADD, CUL3, TRAF2, CASP8, SQSTM1, TNFRSF10B, CBL, MOAP1, RASSF1, TNFRSF10D, TNFRSF10A, TNFSF10, MADD, BCL10, TRADD, RIPK1, DAP3, BTK, CD4, COL2A1, CASP10,
Protein Size: 468 - Poids moléculaire
- 50 kDa
- ID gène
- 8797
- NCBI Accession
- NM_003844, NP_003835
- UniProt
- O00220
- Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
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