TNFRSF10A anticorps (C-Term)

N° du produit ABIN971900

Détail du produit anti-TNFRSF10A anticorps

Antigène: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF10A est non-conjugé

Application: Western Blotting (WB)

Séquence: RAGTAGPGDA LYAMLMKWVN KTGRNASIHT LLDALERMEE RHAKEKIQDL

Homologie: Human: 100%, Mouse: 80%

Attributs du produit: This is a rabbit polyclonal antibody against TNFRSF10A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 468 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNFRSF10A

Antigène: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Autre désignation: TNFRSF10A (TNFRSF10A Produits)

Synonymes: anticorps APO2, anticorps CD261, anticorps DR4, anticorps TRAILR-1, anticorps TRAILR1, anticorps TNFRSF10A, anticorps TNF receptor superfamily member 10a, anticorps tumor necrosis factor receptor superfamily member 26, anticorps tumor necrosis factor receptor superfamily, member 10a, anticorps TNFRSF10A, anticorps LOC510798

Sujet: This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Alias Symbols: APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1
Protein Interaction Partner: UBC, MARCH8, MARCH1, CFLAR, FADD, CUL3, TRAF2, CASP8, SQSTM1, TNFRSF10B, CBL, MOAP1, RASSF1, TNFRSF10D, TNFRSF10A, TNFSF10, MADD, BCL10, TRADD, RIPK1, DAP3, BTK, CD4, COL2A1, CASP10,
Protein Size: 468

Poids moléculaire: 50 kDa

ID gène: 8797

NCBI Accession: NM_003844, NP_003835

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity