CHEK1 anticorps (Middle Region)
Aperçu rapide pour CHEK1 anticorps (Middle Region) (ABIN2779738)
Antigène
Voir toutes CHEK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- CHEK1 Antibody - middle region
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Séquence
- WSCGIVLTAM LAGELPWDQP SDSCQEYSDW KEKKTYLNPW KKIDSAPLAL
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against CHEK1. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CHEK1
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anti-Checkpoint Kinase 1 (CHEK1) (pSer345) antibody
CHEK1 Reactivité: Humain WB, IF, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibodyCHEK1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibodyCHEK1 Reactivité: Humain WB, IHC (p), DB Hôte: Lapin Polyclonal RB7845-RB18425 unconjugated
anti-Checkpoint Kinase 1 (CHEK1) antibodyCHEK1 Reactivité: Humain, Souris WB, ELISA Hôte: Souris Monoclonal 2G1D5 unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer296) antibodyCHEK1 Reactivité: Humain, Souris, Rat WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) antibodyCHEK1 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Monoclonal 2F2 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) antibodyKD Validated CHEK1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB2890 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibodyKD Validated CHEK1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB3390 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) antibodyKD Validated CHEK1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB2815 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibodyCHEK1 Reactivité: Humain IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32589-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Autre désignation
- CHEK1
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Sujet
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Background Information: CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.
Gene Name: Checkpoint kinase 1
Alternative Symbols: CHK1
Protein Name: Serine/threonine-protein kinase Chk1
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Poids moléculaire
- 54kDa
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ID gène
- 1111
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NCBI Accession
- NP_001265
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UniProt
- O14757
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Pathways
- Signalisation p53, Apoptose, Cycle Cellulaire, Réparation de l'ADN
Antigène
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