PTF1A anticorps (N-Term)

N° du produit ABIN2780011

Détail du produit anti-PTF1A anticorps

Antigène: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTF1A est non-conjugé

Application: Western Blotting (WB)

Séquence: FPSPYFDEED FFTDQSSRDP LEDSDELLGD EQAEVEFLSH QLHEYCYRDG

Homologie: Cow: 93%, Dog: 86%, Horse: 92%, Human: 93%, Mouse: 100%, Pig: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Ptf1a. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Ptf1a

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 324 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTF1A

Antigène: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Autre désignation: Ptf1a (PTF1A Produits)

Synonymes: anticorps PTF1A, anticorps PTF1, anticorps si:zc142h2.2, anticorps zgc:112216, anticorps Ptf1a/p48, anticorps XPtf1a, anticorps PTF1-p48, anticorps bHLHa29, anticorps PTF1p48, anticorps pancreas specific transcription factor, 1a, anticorps PTF1A, anticorps ptf1a, anticorps Ptf1a

Sujet: Ptf1a is a transcriptional activator. It binds to the E-box consensus sequence 5'-CANNTG-3' and may play a role in early and late pancreas development and differentiation. Ptf1a plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates and may be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. It is required for the formation of pancreatic acinar and ductal cells. and plays an important role in cerebellar development.
Alias Symbols: PTF1-p48, PTF1p48, bHLHa29
Protein Interaction Partner: Rbpj,
Protein Size: 324

Poids moléculaire: 35 kDa

ID gène: 19213

NCBI Accession: NM_018809, NP_061279

UniProt: Q9QX98

Pathways: Retinoic Acid Receptor Signaling Pathway