ERCC6 anticorps (C-Term)

N° du produit ABIN2780327

Détail du produit anti-ERCC6 anticorps

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC6 est non-conjugé

Application: Western Blotting (WB)

Séquence: EASALLPTTE HDDLLVEMRN FIAFQAHTDG QASTREILQE FESKLSASQS

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ERCC6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human ERCC6

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ERCC6

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Autre désignation: ERCC6 (ERCC6 Produits)

Synonymes: anticorps ARMD5, anticorps CKN2, anticorps COFS, anticorps COFS1, anticorps CSB, anticorps RAD26, anticorps UVSS1, anticorps 4732403I04, anticorps C130058G22Rik, anticorps ercc6, anticorps Ercc6, anticorps ERCC excision repair 6, chromatin remodeling factor, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 6, anticorps excision repair cross-complementation group 6, anticorps DNA excision repair protein ERCC-6, anticorps ERCC6, anticorps Ercc6, anticorps ercc6, anticorps LOC100719487

Sujet: This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544.
Alias Symbols: CSB, CKN2, COFS, ARMD5, COFS1, RAD26, UVSS1
Protein Size: 863

Poids moléculaire: 94 kDa

ID gène: 2074

NCBI Accession: NM_000124, NP_000115

UniProt: Q03468

Pathways: Réparation de l'ADN, Chromatin Binding