ATF4 anticorps (C-Term)

N° du produit ABIN2780378

L’anticorps anti-ATF4 Polyclonal Lapin est utilisé pour la détection de ATF4 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Mouton, Cheval et Saccharomyces cerevisiae. Il a été validé pour WB.

Aperçu rapide pour ATF4 anticorps (C-Term) (ABIN2780378)

Antigène: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Mouton, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATF4 anticorps

Épitope: C-Term

Fonction: ATF4 Antibody - C-terminal region

Séquence: EQNKTAATRY RQKKRAEQEA LTGECKELEK KNEALKERAD SLAKEIQYLK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Sheep: 93%, Yeast: 82%

Attributs du produit: This is a rabbit polyclonal antibody against ATF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ATF4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093901

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATF4

Antigène: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Autre désignation: ATF4

Sujet:

Background Information: ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

Gene Name: Activating transcription factor 4 (tax-responsive enhancer element B67)

Alternative Symbols: CREB2, TXREB, CREB-2, TAXREB67

Protein Name: Cyclic AMP-dependent transcription factor ATF-4

Poids moléculaire: 39kDa

ID gène: 468

NCBI Accession: NP_001666

UniProt: P18848

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response